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Coumestrol, a bioactive found in legumes, was also described for its ability to increase mitochondria biogenesis in cultured muscle cells underlined by an upregulation of electron transport chain proteins and transcriptional regulator of mitochondria biogenesis: PGC 1 and NFR-1 (Seo et al., 2014)

Confirmatory in vivo experiments further demonstrated that the overexpression of MKL-1 in gastric cancer cells indeed resisted the onset of Erastin-induced ferroptosis (Figure S4C-F)

2A and 2Bshow the number of the day post-exposure

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There was no significant difference in the expression of PR protein between groups ( p = 0.796) (Fig